Image of Dr Davide Bruno

Dr Davide Bruno

School of Psychology

Faculty of Health

Email: D.Bruno@ljmu.ac.uk

Telephone: 0151 904 6320

I was born in Italy and graduated in Psychology from the University of Parma, then obtained a PhD from Keele University (2007). After positions at the University of Southampton, the University of Massachusetts, Amherst, the Nathan Kline Institute, New York University, and Liverpool Hope University, I joined Liverpool John Moores University as a Senior Lecturer.

I am now a Reader in Psychology.

My interests are, broadly, memory, ageing and dementia.

You can also find me at: http://dbrunolab.wordpress.com/

Highlighted publications

Bruno D, Grothe MJ, Nierenberg J, Sidtis JJ, Teipel SJ, Pomara N. 2016. Output order and variability in free recall are linked to cognitive ability and hippocampal volume in elderly individuals. Neuropsychologia, 80 :126-132 DOI Author Url Publisher Url Public Url

Bruno D, Grothe MJ, Nierenberg J, Zetterberg H, Blennow K, Teipel SJ, Pomara N. 2015. A study on the specificity of the association between hippocampal volume and delayed primacy performance in cognitively intact elderly individuals. Neuropsychologia, 69 :1-8 DOI Author Url Publisher Url Public Url

Journal article

Bruno D, Jauregi Zinkunegi A, Bock JR, ADNI . 2024. Predicting CDR status over 36 months with a recall-based digital cognitive biomarker Alzheimer's & Dementia: The Journal of the Alzheimer's Association, DOI Author Url Publisher Url Public Url

Frau L, Jonaitis E, Lanhough Kosick R, Zuelsdorff M, Okonkwo O, Bruno D. 2024. The role of cognitive reserve and depression on executive function in older adults: a 10-year study from the Wisconsin Registry for Alzheimer's Prevention The Clinical Neuropsychologist, DOI Author Url Publisher Url Public Url

Bruno D, Jauregi Zinkunegi A, Betthauser T, Carlsson C, Bendlin BB, Okonkwo O, Chin NA, Asthana S, Langhough RE, Johnson SC, Mueller KD. 2024. Story recall performance and AT classification via positron emission tomography: A comparison of Logical Memory and Craft Story 21 Journal of the Neurological Sciences, 464 DOI Author Url Publisher Url Public Url

Reichert Plaska C, Heslegrave A, Bruno D, Ramos-Cejudo J, Han Lee S, Osorio R, Imbimbo BP, Zetterberg H, Blennow K, Pomara N. 2024. Evidence for reduced anti-inflammatory microglial phagocytic response in late-life major depression Brain, Behavior, and Immunity, 120 :248-255 DOI Author Url Publisher Url Public Url

Bruno D, Gicas KM, Jauregi-Zinkunegi A, Mueller KD, Lamar M. 2024. Delayed primacy recall performance predicts post mortem Alzheimer's disease pathology from unimpaired ante mortem cognitive baseline Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 16 DOI Author Url Publisher Url Public Url

Moyo RC, Sigwadhi LN, Carries S, Mkhwanazi Z, Bhana A, Bruno D, Davids EL, Van Hout MC, Govindasamy D. 2024. Health-related quality of life among people living with HIV in the era of universal test and treat: results from a cross-sectional study in KwaZulu-Natal, South Africa HIV Research & Clinical Practice, 25 DOI Author Url Publisher Url Public Url

Teipel SJ, Dyrba M, Kleineidam L, Brosseron F, Levin F, Bruno D, Buerger K, Cosma N, Schneider LS, Düzel E, Glanz W, Fliessbach K, Janowitz D, Kilimann I, Laske C, Munk MH, Maier F, Peters O, Pomara N, Perneczky R, Rauchmann BS, Priller J, Ramirez A, Roy N, Schneider A, Spottke A, Spruth EJ, Roeske S, Wagner M, Wiltfang J, Wolfsgruber S, Bartels C, Jessen F, Heneka MT. 2024. Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 16 :1-12 DOI Author Url Publisher Url Public Url

Nunzio P, Plaska CR, Bruno D, Ramos‐Cejudo J, Osorio RS, Heslegrave A, Pillai A, Imbimbo BP, Zetterberg H, Blennow K. 2023. Sex‐ or depression‐specific relationships with CSF sAPPα, sAPPβ and their associations with CSF sTREM2 in older adults Alzheimer's & Dementia, 19 DOI Publisher Url

Bruno D, Zinkunegi AJ, Bock JR. 2023. Predicting clinical decline over 36 months with a memory‐based digital biomarker Alzheimer's & Dementia, 19 DOI Publisher Url

Jauregi-Zinkunegi A, Langhough R, Johnson SC, Mueller KD, Bruno D. 2023. Comparison of the 10-, 14- and 20-Item CES-D Scores as Predictors of Cognitive Decline Brain Sciences, 13 :1-14 DOI Author Url Publisher Url Public Url

Hale MR, Langhough R, Du L, Hermann BP, Van Hulle CA, Carboni M, Kollmorgen G, Basche KE, Bruno D, Sanson-Miles L, Jonaitis EM, Chin NA, Okonkwo OC, Bendlin BB, Carlsson CM, Zetterberg H, Blennow K, Betthauser TJ, Johnson SC, Mueller KD. 2023. Associations between recall of proper names in story recall and CSF amyloid and tau in adults without cognitive impairment Neurobiology of Aging, 133 :87-98 DOI Author Url Publisher Url Public Url

Bruno D, Jauregi Zinkunegi A, Kollmorgen G, Carboni M, Wild N, Carlsson C, Bendlin B, Okonkwo O, Chin N, Hermann BP, Asthana S, Blennow K, Langhough R, Johnson SC, Pomara N, Zetterberg H, Mueller KD. 2023. A comparison of diagnostic performance of word-list and story recall tests for biomarker-determined Alzheimer's disease Journal of Clinical and Experimental Neuropsychology, :1-7 DOI Author Url Publisher Url Public Url

Jauregi Zinkunegi A, Bruno D. 2023. A comparison of story-recall metrics to predict hippocampal volume in older adults with and without cognitive impairment The Clinical Neuropsychologist, DOI Author Url Publisher Url Public Url

Zinkunegi AJ, Koscik RL, Johnson SC, Mueller KD, Bruno D. 2023. The Total CES‐D score from the 14‐item version as a predictor of cognitive decline Alzheimer's & Dementia, 19 DOI Publisher Url

Frau L, Jonaitis EM, Koscik RL, Zuelsdorff M, Okonkwo OC, Bruno D. 2022. The role of Cognitive Reserve and depression on executive functions in older adults: a 10‐year longitudinal study Alzheimer's & Dementia, 18 DOI Publisher Url

Pomara N, Bruno D, Reichert Plaska C, Ramos Cejudo J, Osorio R, Pillai A, Imbimbo B, Zetterberg H, Blennow K. 2022. Plasma Amyloid-β Dynamics in late-life major depression: A longitudinal study Translational Psychiatry, 12 DOI Author Url Publisher Url Public Url

Mueller K, Du L, Bruno D, Betthauser T, Christian B, Johnson S, Hermann B, Langhough Koscik R. 2022. Item-level story recall predictors of amyloid-beta in late middle-aged adults at increased risk for Alzheimer’s disease Frontiers in Psychology, 13 DOI Author Url Publisher Url Public Url

Bruno D, Jauregi A, Pomara N, Zetterberg H, Blennow K, Koscik R, Carlsson C, Bendlin B, Okonkwo O, Hermann B, Johnson S, Mueller K. 2022. Cross-sectional associations of CSF tau levels with Rey’s AVLT: A recency ratio study Neuropsychology, DOI Author Url Publisher Url Public Url

Frau L, Cazzato V, McGlone FP, Bruno D. 2022. The effects of multimodal training on working memory in younger and older adults The Cognitive Psychology Bullettin, :23-35 DOI Publisher Url Public Url

Teipel S, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma N-C, Dechent P, Dobisch L, Duzel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Pomara N, Preis L, Priller J, Ramirez A, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Jessen F, Heneka M. 2021. Association of cholinergic basal forebrain volume and functional connectivity with markers of inflammatory response in the Alzheimer’s disease spectrum Journal of Alzheimer's Disease, DOI Author Url Publisher Url Public Url

Bruno D, Rutherford A. 2021. Cognitive ability in former professional football (soccer) players is associated with estimated heading frequency Journal of Neuropsychology, DOI Author Url Publisher Url Public Url

Teipel S, Bruno D, Reichert C, Heslegrave A, Ramos-Cejudo J, Osorio R, Zetterberg H, Blennow K, Pomara N. 2021. Association of CSF sTREM2, a marker of microglia activation, with cholinergic basal forebrain volume in major depressive disorder Journal of Affective Disorders, 293 :429-434 DOI Author Url Publisher Url Public Url

Pomara N, Bruno D, Reichert Plaska C, Pillai A, Ramos-Cejudo J, Osorio R, Imbimbo B, Heslegrave A, Zetterberg H, Blennow K. 2021. Evidence of upregulation of the cholinergic anti-inflammatory pathway in late-life depression Journal of Affective Disorders, 286 :275-281 DOI Author Url Publisher Url Public Url

Clark DPA, Bruno D. 2021. EXPRESS: Time is of the essence: Exploring temporal and spatial organisation in episodic memory. Quarterly Journal of Experimental Psychology, DOI Author Url Publisher Url Public Url

Bruno D, Mueller K, Betthauser T, Chin N, Engelman C, Christian B, Koscik R, Johnson S. 2020. Serial position effects in the Logical Memory Test: Loss of primacy predicts amyloid positivity Journal of Neuropsychology, 15 :448-461 DOI Author Url Publisher Url Public Url

Heslegrave AJ, Foiani MS, Bruno D, Reichert C, Zlokovic BV, Huang Y, Zetterberg H, Blennow K, Pomara N. 2020. Microglial activation: A process potentially related to Alzheimer's disease and late‐life major depression Alzheimer's & Dementia, 16 DOI Publisher Url

Pomara N, Bruno D, Reichert C, Lee SH, Sarreal A, Hernando R, Ramos‐Cejudo J, Zetterberg H, Blennow K. 2020. Hypertension accentuates reductions in CSF Aβ42 in elderly depressives Alzheimer's & Dementia, 16 DOI Publisher Url

Talamonti D, Montgomery C, Clark DPA, Bruno D. 2020. Age-related prefrontal cortex activation in associative memory: an fNIRS pilot study. NeuroImage, 222 DOI Author Url Publisher Url Public Url

Mueller K, Koscik R, Du L, Bruno D, Jonaitis E, Koscik A, Christian B, Betthauser T, Chin N, Hermann B, Johnson S. 2020. Proper names from story recall are associated with beta-amyloid in cognitively unimpaired adults at risk for Alzheimer’s disease Cortex, 131 :137-150 DOI Author Url Publisher Url Public Url

Talamonti D, Koscik R, Johnson S, Bruno D. 2020. Temporal contiguity and ageing: The role of memory organization in cognitive decline Journal of Neuropsychology, DOI Author Url Publisher Url Public Url

Bruno D, Reichert Plaska C, Clark D, Zetterberg H, Blennow K, Verbeek M, Pomara N. 2020. CSF α-synuclein correlates with CSF neurogranin in late-life depression The International Journal of Neuroscience, 131 :357-361 DOI Author Url Publisher Url Public Url

Pillai A, Bruno D, Nierenberg J, Pandya C, Feng T, Reichert C, Ramos-Cejudo J, Osorio R, Zetterberg H, Blennow K, Pomara N. 2019. Complement component 3 levels in the cerebrospinal fluid of Cognitively Intact Elderly Individuals with Major Depressive Disorder Biomarkers in Neuropsychiatry, 1 DOI Author Url Publisher Url Public Url

Mueller KD, Koscik RL, Bruno D, Jonaitis E, Koscik AZ, Allison SL, Hermann BP, Christian B, Betthauser TJ, Johnson SC. 2019. O3-03-05: PROPER NOUNS FROM STORY RECALL ARE ASSOCIATED WITH BETA-AMYLOID IN COGNITIVELY UNIMPAIRED ADULTS Alzheimer's & Dementia, 15 :P884-P885 DOI Publisher Url

Pomara N, Bruno D, Petkova E, Reichert C, Zetterberg H, Blennow K, Nierenberg J. 2019. P1‐253: ARE PLASMA AMYLOID‐β LEVELS IN LATE‐LIFE MAJOR DEPRESSION A MARKER OF HEIGHTENED AD RISK? Alzheimer's & Dementia, 15 DOI Publisher Url

Bruno D, Koscik RL, Gleason CE, Pomara N, Betthauser TJ, Chin NA, Engelman CD, Christian BT, Johnson SC. 2019. P3‐464: VARIABILITY IN RECENCY RATIO SCORES IS ASSOCIATED WITH PIB PET AMYLOID LOAD IN DECLINING AND NON‐DECLINING UNIMPAIRED ADULTS Alzheimer's & Dementia, 15 DOI Publisher Url

Talamonti D, Koscik RL, Johnson SC, Bruno D. 2019. P1‐474: MEMORY ORGANIZATION AND AGEING: PREDICTING COGNITIVE DECLINE WITH TEMPORAL CONTIGUITY Alzheimer's & Dementia, 15 DOI Publisher Url

Talamonti D, Koscik R, Johnson S, Bruno D. 2019. Predicting Early Mild Cognitive Impairment With Free Recall: The Primacy of Primacy. Archives of Clinical Neuropsychology, DOI Author Url Publisher Url Public Url

Bruno D, Gleason C, Koscik R, Pomara N, Zetterberg H, Blennow K, Johnson S. 2018. The recency ratio is related to CSF Amyloid Beta 1-42 levels in MCI-AD International Journal of Geriatric Psychiatry, 34 :415-419 DOI Author Url Publisher Url Public Url

Pomara N, Bruno D. 2018. Pathological increases in neuronal hyperactivity in selective cholinergic and noradrenergic pathways may limit the efficacy of Aβ-based interventions in MCI and Alzheimer’s disease Journal of Alzheimer's Disease Reports, 2 :165-167 DOI Author Url Publisher Url Public Url

Bruno D, Koscik R, Woodard J, Pomara N, Johnson S. 2018. The recency ratio as predictor of early MCI International Psychogeriatrics, 30 :1883-1888 DOI Author Url Publisher Url Public Url

Couth S, Stringer G, Leroi I, Sutcliffe A, Gledson A, Bruno D, McDonald K, Montaldi D, Poliakoff E, Rust J, Thompson J, Brown L. 2017. Which computer-use behaviours are most indicative of cognitive decline? Insights from an expert reference group Health Informatics Journal, DOI Author Url Publisher Url Public Url

Bruno D, Nierenberg J, Grothe MJ, Pratico D, Pillai A, Csernansky J, Sershen H, Marmar C, Hashimoto K, Huang Y, Teipel SJ, Zlokovic B, Zetterberg H, Blennow K, Pomara N. 2017. [P4–182]: A NEUROBIOLOGICAL MODEL OF MEMORY IMPAIRMENT IN LATE‐LIFE MAJOR DEPRESSIVE DISORDER Alzheimer's & Dementia, 13 DOI Publisher Url

Pomara N, Bruno D, Nierenberg J, Reichert C, Sarreal A, Hernando R, Csernasky JG, Marmar C, Zetterberg H, Blennow K. 2017. [O1–01–05]: Relationship Between Indices of CSF HPA AXIS Activity and AD Biomarkers in Late Life Depression Alzheimer's & Dementia, 13 DOI Publisher Url

Hashimoto K, Ishima T, Sato Y, Bruno D, Nierenberg J, Marmar CR, Zetterberg H, Blennow K, Pomara N. 2017. Increased levels of ascorbic acid in the cerebrospinal fluid of cognitively intact patients with major depression: a preliminary study Scientific Reports, 7 DOI Author Url Publisher Url Public Url

Gollan JK, Dong H, Bruno D, Nierenberg J, Nobrega JN, Grothe MJ, Pollock BG, Marmar CR, Teipel S, Csernansky JG, Pomara N. 2017. Basal Forebrain Mediated Increase in Brain CRF is Associated with Increased Cholinergic Tone and Depression 'Psychiatry Research: Neuroimaging, DOI Author Url Publisher Url Public Url

Bruno D, Nierenberg J, Cooper T, Marmar C, Zetterberg H, Blennow K, Hashimoto K, Pomara N. 2017. The recency ratio is associated with reduced CSF glutamate in late-life depression Neurobiology of Learning and Memory, 141 :14-18 DOI Author Url Publisher Url Public Url

Kasper E, Brueggen K, Grothe M, Bruno D, Pomara N, Unterauer E, Duering M, Ewers M, Teipel S, Buerger K. 2016. Neuronal correlates of serial position performance in amnestic mild cognitive impairment. Neuropsychology, 30 :906-914 DOI Author Url Publisher Url Public Url

Brueggen K, Kasper E, Dyrba M, Bruno D, Pomara N, Ewers M, Duering M, Buerger K, Teipel S. 2016. The Primacy Effect in Amnestic Mild Cognitive Impairment: Associations with Hippocampal Functional Connectivity Frontiers in Aging Neuroscience, 8 DOI Author Url Publisher Url Public Url

Pomara N, Bruno D, Osorio R, Reichert C, Nierenberg J, Sarreal A, Hernando R, Marmar C, Wisniewski T, Zetterberg H, Blennow K. 2016. State-dependent alterations in CSF Abeta42 levels in cognitively intact elderly with late life major depression Neuroreport, 27 :1068-1071 DOI Author Url Publisher Url Public Url

Bruno D, Ciarleglio A, Grothe M, Nierenberg J, Bachman A, Teipel S, Petkova E, Ardekani B, Pomara N. 2016. Hippocampal volume and integrity as predictors of cognitive decline in intact elderly NeuroReport, 27 :869-873 DOI Author Url Publisher Url Public Url

Brueggen K, Kasper E, Dyrba M, Bruno D, Pomara N, Ewers M, Duering M, Buerger K, Teipel SJ. 2016. IC‐P‐035: Association of Hippocampal Resting State Networks and The Primacy Effect as A Marker of Consolidation in Amnestic MCI Alzheimer's & Dementia, 12 DOI Publisher Url

Brueggen K, Kasper E, Dyrba M, Bruno D, Pomara N, Ewers M, Duering M, Buerger K, Teipel SJ. 2016. P2‐236: Association of Hippocampal Resting State Networks and the Primacy Effect as a Marker of Consolidation in Amnestic MCI Alzheimer's & Dementia, 12 DOI Publisher Url

Pomara N, Bruno D, Reichert C, Sarreal A, Hernando R, Zetterberg H, Blennow K. 2016. P1‐181: State‐Dependent Alterations in CSF Aβ42 Levels in Cognitively‐Intact Elderly With Late Life Major Depression Alzheimer's & Dementia, 12 DOI Publisher Url

Bruno D, Reichert C, Pomara N. 2016. The recency ratio as an index of cognitive performance and decline in elderly individuals Journal of Clinical and Experimental Neuropsychology, 38 :967-973 DOI Author Url Publisher Url Public Url

Young J, Silber T, Bruno D, Galatzer-Levy I, Pomara N, Marmar C. 2016. Is there Progress? An Overview of Select Biomarker Candidates for Major Depressive Disorder Frontiers in Psychiatry, 7 DOI Author Url Publisher Url Public Url

Hashimoto K, Bruno D, Pomara N, Nierenberg J, Marmar C, Zetterberg H, Blennow K. 2016. Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study Translational Psychiatry, 6 DOI Author Url Publisher Url Public Url

Bruno D, Grothe MJ, Nierenberg J, Sidtis JJ, Teipel SJ, Pomara N. 2016. Output order and variability in free recall are linked to cognitive ability and hippocampal volume in elderly individuals. Neuropsychologia, 80 :126-132 DOI Author Url Publisher Url Public Url

Clark DP, Bruno D. 2015. Fit to last: Exploring the longevity of the survival processing effect. Quarterly Journal of Experimental Psychology, DOI Author Url Publisher Url Public Url

Bruno D, Grothe MJ, Nierenberg J, Sidtis J, Teipel SJ, Pomara N. 2015. P2‐211: The association of output order and variability in free recall with cognitive ability and hippocampal volume in elderly individuals Alzheimer's & Dementia, 11 DOI Publisher Url

Pomara N, Bruno D, Ciarleglio A, Constantine A, Reichert C, Zetterberg H, Blennow K, Petkova E, Sidtis J. 2015. P1‐110: Predictors of cognitive decline in elderly depressives Alzheimer's & Dementia, 11 DOI Publisher Url

Kasper E, Brüggen K, Grothe MJ, Bruno D, Pomara N, Duering M, Ewers M, Buerger K, Teipel SJ. 2015. P4‐086: Is hippocampal size associated with primacy recall performance in amnestic mild cognitive impairment? Alzheimer's & Dementia, 11 DOI Publisher Url

Bruno D, Ciarleglio A, Grothe MJ, Nierenberg J, Bachman A, Teipel SJ, Petkova E, Sidtis J, Adrenkani B, Pomara N. 2015. P3‐179: A comparison of hippocampal volume and integrity: Which is the better predictor of cognitive decline? Alzheimer's & Dementia, 11 DOI Publisher Url

Teipel S, Bruno D, Grothe M, Nierenberg J, Pomara N. 2015. Hippocampus and basal forebrain volumes modulate effects of anticholinergic treatment on delayed recall in healthy older adults Alzheimer's & Dementia : diagnosis, assessment & disease monitoring, 1 :216-219 DOI Author Url Publisher Url Public Url

Bruno D, Grothe MJ, Nierenberg J, Teipel SJ, Zetterberg H, Blennow K, Pomara N. 2015. The relationship between CSF tau markers, hippocampal volume and delayed primacy performance in cognitively intact elderly individuals. Alzheimer's & Dementia, 1 :81-86 DOI Author Url Publisher Url Public Url

Bruno D, Grothe MJ, Nierenberg J, Zetterberg H, Blennow K, Teipel SJ, Pomara N. 2015. A study on the specificity of the association between hippocampal volume and delayed primacy performance in cognitively intact elderly individuals. Neuropsychologia, 69 :1-8 DOI Author Url Publisher Url Public Url

Pomara N, Lee SH, Bruno D, Silber T, Greenblatt DJ, Petkova E, Sidtis JJ. 2015. Adverse performance effects of acute lorazepam administration in elderly long-term users: pharmacokinetic and clinical predictors. Progress in Neuropsychopharmacology and Biological Psychiatry, 56 :129-135 DOI Author Url Publisher Url Public Url

Young JJ, Bruno D, Pomara N. 2014. A review of the relationship between proinflammatory cytokines and major depressive disorder. Journal of Affective Disorders, 169 :15-20 DOI Author Url Publisher Url Public Url

Bruno D, Grothe M, Nierenberg J, Teipel S, Pomara N. 2014. P1‐178: HIPPOCAMPAL SIZE PREDICTS DELAYED PRIMACY PERFORMANCE IN COGNITIVELY INTACT ELDERLY PARTICIPANTS Alzheimer's & Dementia, 10 DOI Publisher Url

Lyons M, Healy N, Bruno D. 2014. It takes one to know one: Psychopathy and deception detection Personality and Individual Differences, 60 :S34-S34 DOI Publisher Url

Bruno D, Brown AD, Kapucu A, Marmar CR, Pomara N. 2014. Cognitive reserve and emotional stimuli in older individuals: level of education moderates the age-related positivity effect. Experimental Aging Research, 40 :208-223 DOI Author Url Publisher Url Public Url

Lyons M, Lynch A, Brewer G, Bruno D. 2014. Detection of Sexual Orientation ("Gaydar") by Homosexual and Heterosexual Women ARCHIVES OF SEXUAL BEHAVIOR, 43 :345-352 DOI Author Url Publisher Url

Bruno D, Lyons M, Brewer G. 2014. Response to Bayesian Advice for Gaydar-Based Picking Up: Commentary on Lyons, Lynch, Brewer, and Bruno (2013) by Ploderl ARCHIVES OF SEXUAL BEHAVIOR, 43 :11-12 DOI Author Url Publisher Url

White C, Kapucu A, Bruno D, Rotello C, Ratcliff R. 2013. Memory bias for negative emotional words in recognition memory is driven by effects of category membership Cognition and Emotion, 28 :867-880 DOI Author Url Publisher Url Public Url

Lyons M, Healy N, Bruno D. 2013. It takes one to know one: Relationship between lie detection and psychopathy Personality and Individual Differences, 55 :676-679 DOI Author Url Publisher Url Public Url

Bruno D, Reiss PT, Petkova E, Sidtis JJ, Pomara N. 2013. Decreased recall of primacy words predicts cognitive decline. Archives of Clinical Neuropsychology, 28 :95-103 DOI Author Url Publisher Url Public Url

Pillai A, Bruno D, Sarreal AS, Hernando RT, Saint-Louis LA, Nierenberg J, Ginsberg SD, Pomara N, Mehta PD, Zetterberg H, Blennow K, Buckley PF. 2012. Plasma BDNF Levels Vary in Relation to Body Weight in Females Zhang XY. PLoS ONE, 7 :e39358-e39358 DOI Author Url Publisher Url Public Url

Pomara N, Bruno D, Pillai A, Nierenberg J, Ginsberg S, Petkova E, Sidtis JJ, Mehta P, Zetterberg H, Blennow K, Buckley P. 2012. P2‐012: Circulating Aβ40 influences plasma BDNF levels and white matter integrity Alzheimer's & Dementia, 8 DOI Publisher Url

Bruno D, Pomara N, Nierenberg J, Ritchie JC, Lutz MW, Zetterberg H, Blennow K. 2012. Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants EXPERIMENTAL GERONTOLOGY, 47 :347-352 DOI Author Url Publisher Url

Bruno D, Nierenberg JJ, Ritchie JC, Lutz MW, Pomara N. 2012. Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants PSYCHONEUROENDOCRINOLOGY, 37 :366-371 DOI Author Url Publisher Url

Bruno D. 2012. Predictions in the Brain: Using our Past to Generate a Future MEMORY STUDIES, 5 :96-97 DOI Author Url Publisher Url

Pomara N, Bruno D. 2011. Potential effects of the APOE e2 allele and of family history of Alzheimer's disease on brain amyloid-beta in normal elderly PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108 :E1007-E1007 DOI Author Url Publisher Url

Pomara N, Bruno D, Sidtis JJ, Lutz MW, Greenblatt DJ, Saunders AM, Roses AD. 2011. Translocase of Outer Mitochondrial Membrane 40 Homolog (TOMM40) Poly-T Length Modulates Lorazepam-Related Cognitive Toxicity in Healthy APOE epsilon 4-Negative Elderly JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 31 :544-546 DOI Author Url Publisher Url

Pomara N, Bruno D, Sidtis J, Nierenberg J, Mehta P, Zetterberg H, Blennow K. 2011. P2‐058: CSF Aβ42 reduction in cognitively intact elderly individuals with major depressive disorder Alzheimer's & Dementia, 7 DOI Publisher Url

Pomara N, Bruno D, Sidtis J, Lutz M, Greenblatt D, Saunders A, Roses A. 2011. P1‐255: TOMM40 Poly‐T Variants Influence Sensitivity to Lorazepam‐Induced Impairment in Healthy Elderly Alzheimer's & Dementia, 7 DOI Publisher Url

Pomara N, Bruno D, Nierenberg JJ, Sidtis JJ, Martiniuk FT, Mehta PD, Zetterberg H, Blennow K. 2011. TOMM40 poly-T Variants and Cerebrospinal Fluid Amyloid Beta Levels in the Elderly NEUROCHEMICAL RESEARCH, 36 :1124-1128 DOI Author Url Publisher Url

Pomara N, Bruno D. 2011. Lower plasma β-amyloid levels are associated with moderately greater rate of cognitive decline among older people without dementia Evidence-Based Mental Health, 14 :41 DOI Author Url Publisher Url

Pomara N, Bruno D, Sidtis JJ. 2011. Plasma beta-Amyloid Level, Cognitive Reserve, and Cognitive Decline JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 305 :1655-1655 DOI Author Url Publisher Url

Bruno D, Rutherford A. 2010. How many response options? A study of remember-know testing procedures ACTA PSYCHOLOGICA, 134 :125-129 DOI Author Url Publisher Url

Higham PA, Bruno D, Perfect TJ. 2010. Effects of study list composition on the word frequency effect and metacognitive attributions in recognition memory MEMORY, 18 :883-899 DOI Author Url Publisher Url

Pomara N, Bruno D, Sarreal A, Hernando R, Nierenberg J, Petkova E, Sidtis J, Wisniewski T, Mehta P, Pratico D, Zetterberg H, Blennow K. Lower CSF Amyloid Beta Peptides and Higher F2-Isoprostanes in Cognitively Intact Elderly Individuals With Major Depressive Disorder American Journal of Psychiatry, 169 :523-530 DOI Author Url Publisher Url

Bruno D, Higham PA, Perfect TJ. Global subjective memorability and the strength-based mirror effect in recognition memory Memory and Cognition, 37 :807-818 DOI Author Url Publisher Url

Higham PA, Perfect T, Bruno D. Investigating strength and frequency effects in recognition memory using type-2 signal detection theory Journal of Experimental Psychology: Learning, Memory, and Cognition, 35 :57-80 DOI Author Url Publisher Url

Bruno D, Jauregi Zinkunegi A. The recency ratio assessed by story recall is associated with cerebrospinal fluid levels of neurodegeneration biomarkers Cortex, 159 :167-174 DOI Author Url Publisher Url Public Url

Jauregi Zinkunegi A, Gleason CE, Bendlin B, Okonkwo O, Hermann BP, Blennow K, Zetterberg H, Hogervorst E, Johnson SC, Langhough R, Mueller KD, Bruno D. Menopausal hormone therapy is associated with worse levels of Alzheimer’s disease biomarkers in APOE4-carrying women: An observational study Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Public Url

Jauregi Zinkunegi A, Bruno D. Delayed primacy recall in AVLT is associated with medial temporal tau PET burden in cognitively unimpaired adults. Cortex,

Poster

Bruno D, Zinkunegi AJ, Kollmorgen G, Carboni M, Wild N, Carlsson CM, Bendlin BB, Okonkwo O, Chin NA, Hermann BP, Asthana S, Zetterberg H, Blennow K, Langhough RE, Johnson SC, Mueller KD. 2023. A comparison of word‐list and story recall tests for prediction of biomarker‐determined Alzheimer’s disease

Mueller KD, Basche KE, Bruno D, Frost CM, Christian BT, Betthauser TJ, Johnson SC, Hermann BP, Langhough RE. 2023. Errors and repetitions on tests of language, verbal learning, and memory in cognitively unimpaired adults at increased risk for Alzheimer’s disease

Pomara N, Plaska CR, Bruno D, Cejudo JR, Osorio RS, Pillai A, Heslegrave A, Zetterberg H, Blennow K. 2023. Higher plasma proinflammatory cytokines and reduced microglial TREM2 signaling in Late‐life Major Depression

Bruno D, Reichert C, Zetterberg H, Blennow K, Pomara N. 2022. Higher CSF Ab38 levels protect against cognitive decline in high‐functioning individuals

Hale MR, Koscik RL, Du L, Hermann BP, Van Hulle CA, Suridjan I, Kollmorgen G, Basche KE, Bruno D, Sanson‐Miles L, Jonaitis EM, Chin NA, Okonkwo OC, Bendlin BB, Carlsson CM, Zetterberg H, Blennow K, Betthauser TJ, Johnson SC, Mueller KD. 2022. Associations between semantic memory for proper names in story recall and CSF amyloid and tau in a cognitively unimpaired sample

Bruno D, Rutherford A. 2021. Cognitive performance in former professional football (soccer) players is affected by estimated heading frequency

preprint

Bruno D, Gicas KM, Jauregi Zinkunegi A, Mueller KD, Lamar M. 2023. Delayed primacy recall performance predicts post mortem Alzheimer's disease pathology from unimpaired ante mortem cognitive baseline. DOI Author Url Publisher Url

Jauregi Zinkunegi A, Langhough R, Johnson S, Mueller K, Bruno D. 2023. Comparison of the 10-, 14- and 20-Item CES-D Scores as Predictors of Cognitive Decline Preprints.org DOI Publisher Url

Mueller K, Koscik R, Du L, Bruno D, Jonaitis E, Koscik A, Christian B, Betthauser T, Chin N, Hermann B, Johnson S. 2020. Proper names from story recall are associated with beta-amyloid in cognitively unimpaired adults at risk for Alzheimer's disease bioRxiv DOI Publisher Url

Dataset

Talamonti D, Clark D, Bruno D. 2022. Age-related differences in spatial and temporal clustering of episodic memory DOI Public Url

Bruno D, Rutherford A. 2021. Football heading

Talamonti D, Clark D, Montgomery C, Bruno D. 2020. Age-related prefrontal cortex activation in associative memory: an fNIRS pilot study DOI Public Url

Conference publication

Pomara N, Plaska CR, Bruno D, Ramos-Cejudo J, Osorio RS, Heslegrave A, Pillai A, Imbimbo B, Zetterberg H, Blennow K. 2022. Sex-Specific Association of Amyloid Precursor Protein With Microglial Activation and Modulation by Apolipoprotein E Genotype in Major Depressive Disorder NEUROPSYCHOPHARMACOLOGY, 47 :67-67

Pomara N, Plaska CR, Ramos-Cejudo J, Bruno D, Osorio R, Heslegrave A, Pillai A, Zetterberg H, Blennow K. 2021. Longitudinal Increase in CSF sTREM2 is Associated With Increased Markers of CSF AD Pathology in Late-Life Major Depression Potentially Reflecting a Compensatory Mechanism NEUROPSYCHOPHARMACOLOGY, 46 :236-237

Pomara N, Bruno D, Nierenberg J, Reichert C, Fu M, Zetterberg H, Blennow K. 2019. CSF butyrylcholinesterase and acetyl-cholinesterase activity and their relationship to pro-inflammatory cytokines in late-life major depression EUROPEAN NEUROPSYCHOPHARMACOLOGY, 31st Congress of the European-College-of-Neuropsychopharmacology (ECNP) 29 :S79-S80 DOI Author Url Publisher Url

Pomara N, Bruno D, Reichert C, Sershen H, Zetterberg H, Blennow K, Verbeek M. 2019. Cerebrospinal Fluid Alpha-Synuclein in Late-Life Depression and Neurobiological Correlates NEUROPSYCHOPHARMACOLOGY, 44 :315-316

Pomara N, Bruno D, Nierenberg J, Reichert C, Fu M, Brundage K, Zetterberg H, Blennow K. 2018. CSF Acetylcholinesterases: Relationship to Peripheral and CSF Pro-Inflammatory Cytokines in Late-Life Major Depression NEUROPSYCHOPHARMACOLOGY, 43 :S138-S139

Pomara N, Bruno D, Nierenberg J, Zetterberg H, Blennow K, Heslegrave A, Foiani M. 2017. Reduction in CSF sTREM2, a Biomarker of Microglia Activation, in Elderly Depressives NEUROPSYCHOPHARMACOLOGY, 56th Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP) and Cognitive-Neuroscience-Society 42 :S409-S409 Author Url

Pomara N, Nierenberg J, Bruno D, Reichert C, Osorio R, Sarreal A, Hernando R, Marmar C, Wisniewski T, Zetterberg H, Blennow K. 2016. Selective and State-Dependent Changes in CSF Abeta42 Levels in Cognitively-Intact Elderly With Late Life Major Depression NEUROPSYCHOPHARMACOLOGY, 41 :S544-S544 Author Url

Pomara N, Bruno D, Ciarleglio A, Constantine A, Reichert C, Petkova E, Zetterberg H, Blennow K. 2015. Biomarkers of Cognitive Decline in Elderly Depressives NEUROPSYCHOPHARMACOLOGY, 54th Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP) 40 :S327-S327 Author Url

Pomara N, Bruno D, Reichert C, Nierenberg J, Sidtis JJ, Martiniuk FT, Zetterberg H, Blennow K. 2013. Chemokine-specific Relationships to AD Biomarkers in CSF in Healthy Older Adults NEUROPSYCHOPHARMACOLOGY, 38 :S164-S164 Author Url

Frau L, Cazzato V, McGlone F, Bruno D. A novel drug-free intervention to improve cognitive performance in unimpaired older participants: the power of affective touch Alzheimer's Association International Conference (AAIC) DOI Publisher Url

Thesis/Dissertation

Provazza S. 2021. VISUAL AND PHONOLOGICAL PROCESSING IN DEVELOPMENTAL DYSLEXIA: A CROSS-LINGUISTIC INVESTIGATION Adams AM, Roberts D, Bruno D. Public Url

Talamonti D. 2019. Input and output order of recall as early markers of cognitive decline Bruno D, Ogden R, Forshaw M, Clark D. Public Url

Editorial/letter to the editor

Rutherford A, Stewart W, Bruno D. 2017. Heading for trouble: is dementia a game changer for football? British Journal of Sports Medicine, 53 DOI Author Url Publisher Url Public Url

Tawfik H, Bruno D. 2016. Editorial International Journal of Medical Informatics, 91 :74-74 DOI Publisher Url

Tawfik H, Bruno D. 2016. Editorial International Journal of Medical Informatics, 91 DOI

Pomara N, Bruno D. Major depression may lead to elevations in potentially neurotoxic amyloid beta species independently of Alzheimer’s disease American Journal of Geriatric Psychiatry, DOI Author Url Publisher Url

Pomara N, Bruno D. Basal Forebrain Resting Functional Activity Associated with Brain Amyloid-β Burden in ε4 Carriers and Older Women: Possible Implications for Baseline Cognition and Response to Amyloid-β-based Preventive Trials Radiology, DOI Author Url Publisher Url

Bruno D, Busse' C, Cagnin A. Effective discrimination with the recency ratio between Alzheimer’s disease and dementia with Lewy bodies Journal of Alzheimer's Disease,

Books (authored)

Bruno D. 2015. The preservation of memory :1-231 DOI Publisher Url

Chapters

Bruno D, Rutherford A. The effects of normal and pathological aging on memory The Preservation of Memory: Theory and Practice for Clinical and Non-Clinical Populations DOI

Bruno D, Renner D, Barrett-Baxendale M, Reid D, Tawfik H. Augmenting familiar appliances to assist people living with dementia The Preservation of Memory: Theory and Practice for Clinical and Non-Clinical Populations DOI

Bruno D, Rutherford A, Markopoulos G, Van Den Bos M. Long-term memory: encoding to retrieval Cognitive Psychology

Public engagement:

Public talk or lecture, Researchers, but anyone can view, Speaker, Talk on Youtube via Dementia Researcher, https://www.youtube.com/watch?v=v8bt4JjK6Zs. 2023

Public talk or lecture, University of Third Age, Lecturer, Chester, Dementia lecture. 2020

Other, General public, experts in dementia, researcehrs, people with dementia, Talk and organisation committee, Representative for LJMU, Salford University, North West Dementia ARUK Public Engagement. 2017

Public talk or lecture, General public, stakeholders, charities, community support, Speaker, Blacon, Cheshire, Dementia talks/meetings at Vintage Blacon (Community Group), Blacon, Chester. 2013

Media Coverage:

I was quoted by more than 30 outlets for comments on paper by Brickman et al. (2023; PNAS) on flavanols and memory. See ex.: https://inews.co.uk/news/science/green-tea-apples-pears-reverse-age-related-memory-decline-catch-2372487; and https://edition.cnn.com/2023/05/29/health/cocoa-flavanols-memory-study-wellness/index.html 2023

Football heading and dementia - Euronews (TV interview) 2021

Radio Interview, Radio New Zealand (Football heading and Dementia) 2021

Heading the ball is linked to cognitive impairment 2021
www.australiantimes.co.uk
theconversation.com
free-mail.co.za

Forgetting the start of a story may be a sign of dementia - reported in various news outlets and BBC Merseyside, up to 7mil readership 2020
uk.yahoo.com
www.irishexaminer.com
more.talktalk.co.uk

Alzheimer’s disease – don’t give up on plaque-busting drugs just yet 2018

Editorial on British Medical Journal Blogs - British Journal of Sport Medicine blog. Title: Heading for trouble: is dementia a game changer for football?

Forgetting first words on a list may signal mental decline, written by Rachael Rettner. Based on Bruno et al. (2013). Archives of Clinical Neuropsychology. Published on Fox News and other outlets.

Alzheimer’s biomarkers linked to major depression, written by Deborah Brauser. Based on Pomara, Bruno et al. (2012). American Journal of Psychiatry. Published on Medscape Today News

Are lesbians less into casual sex than hetero women?, written by Zhana Vrangalova. Based on Lyons, …, Bruno (2014). Archives of Sexual Behavior. Published on Psychology Today.

Award:

Principal Investigator for LJMU: 2020-2025 - $1,400,000 ($216,770 direct funding) for a project titled “Novel story recall measures as indicators of cognitive decline associated with Alzheimer’s disease and related disorders biomarkers: a collaborative study of existing data” (R01 AG070940-01). NIA-NIH (USA), National Institute of Health. 2021

Developing and validating a survey method for determining amount of football heading done over a football career Grant – Co-Investigator: 2018 - ¥997,001, The Univers Foundation (Japan). 2018

Best Poster: Second Prize at the 2nd Annual NYU Center of Excellence on Brain Aging Research Day. 2011

Experimental Psychological Society: Grindley Grant. 2006

Other invited event:

What does the serial position curve tell us about dementia risk?, Liverpool Hope University, Nov 2018, External Speaker: What does the serial position curve tell us about dementia risk? Department of Psychology, Liverpool Hope University, England, UK.. 2018

BPS Cognitive Conference, Liverpool, Proponent and Chair of Symposium on Cognitive Ageing.. 2018

6th International Conference on Memory, Budapest, Hungary, Symposium on “Memory Preservation and Decline”. 2016

BPS General Conference, Nottingham, UK, Invited to speak at Symposium. Talk title: "A longitudinal study of plasma Amyloid-β levels in late-life major depression". 2016

Ageing and memory: Tracking change to predict decline, Keele University, Invited talk. 2014

Teaching qualification:

Higher Education Associate Teacher Certificate. 2004

Editorial boards:

Associate Editor for Geriatrics (2020-present).

Journal of Neuropsychology, Associated Editor.

Review Editor for Frontiers in Psychology (2021-present).

Fellowships:

Fellow of the Higher Education Academy, Higher Education Academy.

External collaboration:

Keele University, Dr Andrew Rutherford.

Nathan Kline Institute and New York University, Dr Nunzio Pomara.

University of Gothenburg, Dr henrik Zetterberg & Dr Kaj Blennow.

University of Manchester, Dr Iracema Leroy.

University of Padova, Annachiara Cagnin.

University of Rostock, Dr Stefan Teipel.

University of Wisconsin, Madison, Dr Rebecca Koscik & Dr Sterling Johnson (5)..

Conference organisation:

Liverpool Neuroscience Day, June 2019.

Liverpool Neuroscience Winter Gala, November 2019.

Symposium on “Health Informatics for Active Ageing and People with Dementia”. Liverpool Hope University, July 2014.

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