Connor’s PhD work is within the field of exercise proteomics and aims to investigate how the molecular responses to acute exercise culminate in the long-term adaptations that enhance muscle mass and function.
PhD Project Title: Dynamic proteomic analysis of skeletal muscle adaptations to exercise.
Supervisors: Prof. Jatin G Burniston, Prof. Stuart M Phillips, Dr. Ivo Siekmann
Degrees
2020, Liverpool John Moores University, UK, MSc Exercise Physiology
2019, Liverpool John Moores University, UK, BSc (Hons) Sport & Exercise Science
Journal article
Thomas ACQ, Stead CA, Burniston JG, Phillips SM. 2024. Exercise-specific adaptations in human skeletal muscle: Molecular mechanisms of making muscles fit and mighty Free Radical Biology and Medicine, 223 :341-356 DOI Author Url Publisher Url Public Url
Srisawat K, Stead CA, Hesketh K, Pogson MA, Strauss JA, Cocks MS, Siekmann I, Phillips SM, Lisboa PJ, Shepherd SO, Burniston JG. 2023. People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training Proteomics, :1-14 DOI Author Url Publisher Url Public Url
Nishimura Y, Bittel AJ, Stead CA, Chen Y-W, Burniston JG. 2023. Facioscapulohumeral muscular dystrophy is associated with altered myoblast proteome dynamics Molecular & Cellular Proteomics, 22 DOI Author Url Publisher Url Public Url
Hesketh SJ, Stansfield BN, Stead CA, Burniston JG. 2021. The application of proteomics in muscle exercise physiology Expert Review of Proteomics, 17 :813-825 DOI Author Url Publisher Url Public Url
Stead CA, Hesketh SJ, Bennett S, Sutherland H, Jarvis JC, Lisboa PJ, Burniston JG. 2020. Fractional Synthesis Rates of Individual Proteins in Rat Soleus and Plantaris Muscles. Proteomes, 8 DOI Author Url Publisher Url Public Url
Rudhun LM, Aaron T, Stead C, Hesketh S, Sutherland H, Burniston J, Jarvis J. The effect of programmed resistance training on the muscle myofibrillar proteome Graduate Journal of Sports Science, Coaching, Management, & Rehabilitation, 1 :34-34 DOI Publisher Url
Thesis/Dissertation
Stead C. 2024. Dynamic proteomic analysis of skeletal muscle adaptations to exercise training Burniston J, Phillips S, Siekmann I. Public Url
preprint
Stansfield BN, Barrett JS, Bennett S, Stead CA, Pugh J, Shepherd SO, Strauss JA, Louis J, Close GL, Lisboa PJ, Burniston JG. 2024. Turnover rates of human muscle proteins in vivo reported in fractional, mole and absolute units Cold Spring Harbor Laboratory DOI Publisher Url
Srisawat K, Stead C, Hesketh K, Pogson M, Strauss J, Cocks M, Siekmann I, Phillips S, Lisboa P, Shepherd S, Burniston J. 2023. Muscle of obese insulin-resistant humans exhibits losses in proteostasis and attenuated proteome dynamics that are improved by exercise training bioRxiv DOI Publisher Url
Srisawat K, Stead C, Hesketh K, Pogson M, Strauss J, Cocks M, Siekmann I, Phillips S, Lisboa P, Shepherd S, Burniston J. 2023. People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training Authorea Preprints DOI Publisher Url
Nishimura Y, Bittel A, Stead C, Chen Y-W, Burniston J. 2022. Facioscapulohumeral muscular dystrophy is associated with altered myoblast proteome dynamics bioRxiv DOI Publisher Url
Conference publication
Burniston J, Barrett J, Bennett S, Stead C, Louis J, Close G, Lisboa P. 2020. Dynamic Proteome Profiling of Protein Fractional and Molar Synthesis Rates in Human Muscle
Award:
Tom Reilly Award, LJMU. 2019