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Connor Stead

Sport and Exercise Sciences

Faculty of Science

Connor’s PhD work is within the field of exercise proteomics and aims to investigate how the molecular responses to acute exercise culminate in the long-term adaptations that enhance muscle mass and function.

PhD Project Title: Dynamic proteomic analysis of skeletal muscle adaptations to exercise.

Supervisors: Prof. Jatin G Burniston, Prof. Stuart M Phillips, Dr. Ivo Siekmann

Degrees

2020, Liverpool John Moores University, UK, MSc Exercise Physiology
2019, Liverpool John Moores University, UK, BSc (Hons) Sport & Exercise Science

Journal article

Thomas ACQ, Stead CA, Burniston JG, Phillips SM. 2024. Exercise-specific adaptations in human skeletal muscle: Molecular mechanisms of making muscles fit and mighty Free Radical Biology and Medicine, 223 :341-356 DOI Author Url Publisher Url Public Url

Srisawat K, Stead CA, Hesketh K, Pogson MA, Strauss JA, Cocks MS, Siekmann I, Phillips SM, Lisboa PJ, Shepherd SO, Burniston JG. 2023. People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training Proteomics, :1-14 DOI Author Url Publisher Url Public Url

Nishimura Y, Bittel AJ, Stead CA, Chen Y-W, Burniston JG. 2023. Facioscapulohumeral muscular dystrophy is associated with altered myoblast proteome dynamics Molecular & Cellular Proteomics, 22 DOI Author Url Publisher Url Public Url

Hesketh SJ, Stansfield BN, Stead CA, Burniston JG. 2021. The application of proteomics in muscle exercise physiology Expert Review of Proteomics, 17 :813-825 DOI Author Url Publisher Url Public Url

Stead CA, Hesketh SJ, Bennett S, Sutherland H, Jarvis JC, Lisboa PJ, Burniston JG. 2020. Fractional Synthesis Rates of Individual Proteins in Rat Soleus and Plantaris Muscles. Proteomes, 8 DOI Author Url Publisher Url Public Url

Thesis/Dissertation

Stead C. 2024. Dynamic proteomic analysis of skeletal muscle adaptations to exercise training Burniston J, Phillips S, Siekmann I. Public Url

preprint

Srisawat K, Stead C, Hesketh K, Pogson M, Strauss J, Cocks M, Siekmann I, Phillips S, Lisboa P, Shepherd S, Burniston J. 2023. Muscle of obese insulin-resistant humans exhibits losses in proteostasis and attenuated proteome dynamics that are improved by exercise training bioRxiv DOI Publisher Url

Nishimura Y, Bittel A, Stead C, Chen Y-W, Burniston J. 2022. Facioscapulohumeral muscular dystrophy is associated with altered myoblast proteome dynamics bioRxiv DOI Publisher Url

Conference publication

Burniston J, Barrett J, Bennett S, Stead C, Louis J, Close G, Lisboa P. 2020. Dynamic Proteome Profiling of Protein Fractional and Molar Synthesis Rates in Human Muscle in vivo FASEB JOURNAL, Annual Meeting on Experimental Biology 34 DOI Author Url Publisher Url

Award:

Tom Reilly Award, LJMU. 2019

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