Dr Kate Phillips

Conference publication

Keenan R, Phillips K. 2019. CCL21 and Dendritic Cell Suppression in Paediatric B Cell Acute Lymphoblastic Leukaemia Blood, American Society of Hematology 134 :3959-3959 DOI Author Url Publisher Url

Phillips KL, Hansen A, Littler A, Smith L, Keenan R. 2018. Hydroxyurea treated children with Sickle Cell Disease can safely stop folic acid supplementation BRITISH JOURNAL OF HAEMATOLOGY, 58th Annual Scientific Meeting of the British-Society-for-Haematology 181 :124-125 Author Url

Phillips KL, Ashmore L, Karpha I, Smith L, Keenan R. 2018. Early commencement of Hydroxyurea therapy in children with sickle cell disorders prevents high risk Trans-Cranial Doppler development BRITISH JOURNAL OF HAEMATOLOGY, 58th Annual Scientific Meeting of the British-Society-for-Haematology 181 :121-122 Author Url

Smith L, Littler A, Phillips KLE, Keenan RD. 2017. Stopping Folic Acid Supplementation in Hydroxyurea Treated Children with Sickle Cell Disease Blood, American Society of Hematology Annual Meeting

Karpha I, Smith L, Abernathy L, Phillips KLE, Keenan RD. 2017. Hydroxyurea Therapy Prevents High Risk Trans-Cranial Doppler Development in Children with Sickle Cell Disorders Blood, American Society of Hematology

Phillips K, Dean JE, Flanagan BF, Christmas SE, Keenan RD. 2016. Potential for Dendritic Cell Stimulated De Novo Anti-Leukaemia CD4 T Cell Response in the Bone Marrow Tumour Microenvironment during Induction Chemotherapy Blood, American Society of Haematology :2524-2524

Phillips KLE, Flanagan BF, Christmas SE, Keenan RD. 2016. Characterising the immune phenotype of paediatric acute lymphoblastic leukaemia patients during induction chemotherapy BRITISH JOURNAL OF HAEMATOLOGY, 36th World Congress of the International-Society-of-Hematology, British Society of Haematology 173 :77-77

Smith L, Phillips KLE, Keenan RD. 2016. Higher dose hydroxyurea/hydroxycarbamide therapy for sickle cell disorders in childhood: The experience of Alder Hey Children’s Hospital BRITISH JOURNAL OF HAEMATOLOGY, 36th World Congress of the International-Society-of-Hematology, British Society of Haematology 173 :150-150 Author Url

Phillips KLE, Flanagan BF, Christmas SE, Keenan RD. 2016. T lymphocyte reconstitution during induction chemotherapy in paediatric B-cell acute lymphoblastic leukaemia BRITISH JOURNAL OF HAEMATOLOGY, 36th World Congress of the International-Society-of-Hematology, British Society of Haematology 173 :77-78

Phillips KLE, Christmas SE, Flanagan BF, Keenan RD. 2015. Application of Human Immunophenotyping Consortium Panels to Early Childhood Leukaemia; From Diagnosis to End of Induction Chemotherapy BLOOD, 57th Annual Meeting of the American-Society-of-Hematology 126

Smith L, Phillips KLE, Keenan RD. 2015. Hydroxyurea Therapy for Sickle Cell Disorders in Childhood: Adherence to Therapy Transforms Lives and Needs to be the Focus - the Experience of Alder Hey Children’s Hospital BLOOD, 57th Annual Meeting of the American-Society-of-Hematology 126

Phillips KLE, Christmas SE, Flanagan BF, Keenan RD. 2015. Normal Lymphocytes at Diagnosis and during Induction Chemotherapy in Childhood Acute Lymphoblastic Leukaemia in Peripheral Blood and Bone Marrow Are Predominantly CD3+, CD4+or CD8+, CCR7+, CD45RA+, HLA-DR- BLOOD, 57th Annual Meeting of the American-Society-of-Hematology 126

Edwin C, Dean J, Keenan R, McNamara P, Phillips K. 2015. The presence of non-tumour T and B lymphocytes in diagnostic bone marrow is associated with improved overall survival in childhood common acute lymphoblastic leukaemia BRITISH JOURNAL OF HAEMATOLOGY, 55th Annual Scientific Meeting of the British-Society-for-Haematology 169 :14-14 Author Url

Daniels J, Binch ALA, Dunn S, Phillips K, Chiverton N, Cole A, Michael AR, Brakewell L, Le Maitre CL. 2014. Human Degenerate Discs Show Increased Activation of Intracellular Signalling Pathways of IL-1 Global Spine Journal, World Form for Spine Research :27-27 Publisher Url

Binch ALA, Phillips K, Chiverton N, Cole A, Michael AR, Brakewell L, Cross AK, Le Maitre CL. 2014. Role of Semaphorins in Angiogenesis and Innervation in Human Intervertebral Disc Degeneration Global Spine Journal, World Forum for Spine Research :25-25 Publisher Url

Estevao ACB, Phillips KLE, Chiverton N, Cole A, Michael A, Breakwell L, Cross AK, Le Maitre CL. 2012. CXCL1, CXCL2 and CXCL3 in the Pathogenesis of Intervertebral Disc Degeneration JOURNAL OF PATHOLOGY, 228 :S30-S30

Phillips KLE, Chiverton N, Cole A, Michael A, Breakwell L, Haddock G, Bunning RAD, Cross AK, Le Maitre CL. 2012. Chemokines and their Receptors in the Human Intervertebral Disc JOURNAL OF PATHOLOGY, 228 :S30-S30

Daniels J, Phillips KL, Cole A, Michael A, Breakwell L, Chiverton N, Le Maitre CL. 2012. Differential Intracellular Signalling Pathways Induced by IL-1 and CDMP-1 in Human Nucleus Pulposus Cells, and their Potential as Therapeutic Targets. JOURNAL OF PATHOLOGY, 228 :S17-S17

Phillips KLE, Chiverton N, Cole A, Michael A, Breakwell L, Haddock G, Bunning RAD, Cross AK, Le Maitre CL. 2012. Interleukin-1 Regulates Chemokine Expression in the Human Intervertebral Disc JOURNAL OF PATHOLOGY, 228 :S30-S30

Thomas S, Colletta R, Phillips K, Chiverton N, Cole A, Michael AR, Breakwell L, Cross A, Le Maitre C. 2012. Regulation of Neurotrophic Factor Expression in Nerve Cells and Intervertebral Disc Cells by Inflammatory Cytokines, Implications for Pain Pathways. JOURNAL OF PATHOLOGY, 228 :S18-S18

Phillips KLE, Chiverton N, Bunning RD, Haddock G, Cross AK, Le Maitre CL. 2012. CYTOKINE AND CHEMOKINE EXPRESSION PROFILE IN HUMAN INTERVERTEBRAL DISC DEGENERATION RHEUMATOLOGY, 51 :147-147

Daniels J, Phillips KLE, Chiverton N, Le Maitre CL. 2012. INTRACELLULAR SIGNALLING MECHANISMS INDUCED BY IL-1 IN HUMAN NUCLEUS PULPOSUS CELLS RHEUMATOLOGY, 51 :145-145 Author Url

Phillips KLE, Cross A, Chiverton N, Haddock G, Bunning RAD, Le Maitre CL. 2012. ROLE OF CYTOKINES AND CHEMOKINES IN HUMAN INTERVERTEBRAL DISC DEGENERATION RHEUMATOLOGY, 51 :147-147

Daniels J, Phillips K, Chiverton N, Le Maitre CL. 2012. Differential Intracellular Signaling Pathways Are Activated by Catabolic and Anabolic Factors in the IVD, and these Could be Targeted in Selected Therapeutic Approaches Global Spine Journal, World Forum for Spine Research S2 :64-64 Publisher Url

Phillips K, Chiverton N, Haddock G, Bunning RAD, Cross AK, Le Maitre CL. 2012. Human Intervertebral Disk Degeneration is Associated with Increased Chemokine Expression Global Spine Journal, World Forum for Spine Research S2 :69-69 Publisher Url

Phillips K, Chiverton N, Haddock G, Bunning RAD, Cross AK, Le Maitre CL. 2012. Regulation of Chemokine Expression by Interleukin-1 in Human Intervertebral Disk Degeneration Global Spine Journal, World Forum of Spine Research S2 :68-68 Publisher Url

Thomas S, Colletta R, Phillips K, Chiverton N, Cross AK, Le Maitre CL. 2012. Regulation of Neurotrophic Factor Expression in Nerve Cells and Intervertebral Disk Cells by Inflammatory Cytokines, Implications for Pain Pathways Global Spine Journal, World Forum for Spine Research S2 :10-10 Publisher Url

Journal article

Phillips KL, Wright N, McDermott E, Cross NA. 2019. TRAIL responses are enhanced by nuclear export inhibition in osteosarcoma Biochemical and Biophysical Research Communications, 517 :383-389 DOI Author Url Publisher Url

Phillips KLE, Healy L, Smith L, Keenan RD. 2017. Hydroxyurea Therapy in UK Children with Sickle Cell Anaemia – A Single Centre Experience Pediatric Blood and Cancer, 65 DOI Author Url Publisher Url Public Url

Edwin C, Dean J, Bonnett L, Phillips K, Keenan R. 2016. Non-tumour bone marrow lymphocytes correlate with improved overall survival in childhood acute lymphoblastic leukaemia. Pediatric Blood and Cancer, 63 :1848-1851 DOI Author Url Publisher Url Public Url

Phillips KLE, Cullen K, Chiverton N, Michael ALR, Cole AA, Breakwell LM, Haddock G, Bunning RAD, Cross AK, Le Maitre CL. 2015. Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes. Osteoarthritis Cartilage, 23 :1165-1177 DOI Author Url Publisher Url

Phillips K, Phillips KL, Jordan-Mahy N, Nicklin MJ, CL LM. 2013. Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration. DOI Author Url Publisher Url

Phillips K, Wang H, Tian Y, Wang J, Phillips KL, Binch AL, Dunn S, Cross A, Chiverton N, Zheng Z, Shapiro IM, CL LM, Risbud MV. 2013. Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration. DOI Author Url Publisher Url

Phillips K, Phillips KL, Chiverton N, Michael AL, Cole AA, Breakwell LM, Haddock G, Bunning RA, Cross AK, CL LM. 2013. The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc. DOI Author Url Publisher Url

Phillips K, Wang J, Tian Y, Phillips KL, Chiverton N, Haddock G, Bunning RA, Cross AK, Shapiro IM, CL LM, Risbud MV. 2013. Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1. DOI Author Url Publisher Url